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Parkinson’s disease is the second most common neurodegenerative disease after Alzheimer’s, affecting about one million people in the United States and an estimated four million worldwide. The Center for Disease Control rated complications from Parkinson’s disease as the 14th leading cause of death in the United States. The prevalence of the disease is expected to increase substantially in the next 20 years due to the aging of the population in the U.S., Europe and globally, as well as an increase in the age-related incidence of the disease. The economic burden of Parkinson’s disease is estimated to be $6 billion annually in the U.S. Learn more about Parkinson's disease. For over half a century, the National Parkinson Foundation (NPF) has focused on meeting the needs in the care and treatment of people with Parkinson’s disease (PD). NPF has funded more than $180 million in care, research and support services.